肝移植术后胆道并发症病因分析

Etiological analysis of biliary complications after liver transplantation

目的探讨原位肝移植术后胆道并发症的病因。方法回顾性分析235例尸体供肝和36例活体供肝原位肝移植的临床资料,总结术后胆道并发症的病因。结果 36例活体肝移植受体术后胆道并发症的发生率为5.6%,235例尸体供肝肝移植受体术后胆道并发症的发生率为19.1%;肝内胆道狭窄和胆道铸型结石形成等严重胆道并发症在活体肝移植中未发生。讨论缺血时间尤其热缺血时间是导致严重胆道并发症的最主要的原因,所留取的受体胆道长度也是影响胆道并发症的一个主要因素。

Objective To explore the etiology of biliary complications after orthotopie liver transplantation （OLT）. Methods The clinical data of 235 patients receiving eadaverie whole organ liver transplantation and 36 undergoing living donor liver transplantation （LDLT） in our hospital were retrospectively analyzed. Results Of the 36 patients receiving LDLT, 2 had biliary complications （5.6%） and the complications included leakage from the cut surface of the liver and anastomotie stricture. Amongst the 235 patients undergoing eadaverie whole organ liver transplantation, 45 had biliary complications （19.1%）. Conclusions Donor warm isehemie time may predispose the recipients to an increased incidence of biliary complications.