原发性肝癌栓塞后Ⅱ期手术切除与单纯栓塞治疗的疗效比较

A Comparative Study of Secondary Resection after TAE and Repeated TAE for the Treatment of Hepatocellular Carcinoma

本文分析５０例（甲组）非手术治疗的中晚期肝癌行ＴＡＥ后二期手术切除的临床疗效，并将生存率及肿瘤复发情况与４２例（乙组）单纯重复行ＴＡＥ治疗的中晚期肝癌相比较。结果：甲组一、二年累计生存率分别为７１％、５０％，乙组为７３％和４３％，二组间无显著差异。甲组ＯｋｕｄａⅠ期患者的生存率优于乙组，而ＯｋｕｄａⅡ期患者的生存率乙组优于甲组。认为中晚期肝癌行ＴＡＥ后二期手术切除的必要性尚有待讨论，二期切除不能改善ＯｋｕｄａⅡ期患者的生存情况。

Objective. To study the alternative treatment of unresectable hepatocellular carcinoma.Matrials and methods. 50 patients with unresectable hepatocellular carcinoma(HCC) underwent secondary resection after TAE(Group A)and 42 patients with HCC were treated with repeated TAE(Groupp B).The therapeutic results obtained in two groups were retrospective analyzed and compared.Results. The 1-year,2-year cumulative survival rates of Group A were 71% and 50%,respectively. However, the rate were 73% and 43%, respectively, for the patients in Group B;these differences were not statistically significant. The cumulative survival in patients in Okuda' stage Ⅰ of Group A were significantly longer than that of Group B. In contrast,the survival rate of patients in Okuda's stage Ⅱ of Group A were worse than that of Group B.Conclusion. These results indicate that the secondary surgery after TAE for unresctable hepatocellular carcinoma should be well discussed.This treatment can not offer nore favorable results in patients in Okuda's stage Ⅱ compared with repeated TAE.