肠易激综合征的胆囊收缩功能

Gallbladder Contractive Function in Patients with Irritable Bowel Syndrome

本文对１５例肠易激综合征（ＩＢＳ）和１０例健康对照的胆囊收缩功能进行了研究。应用超声显像测定了以下参数：（１）空腹胆囊容积（ＦＧＶ），（２）服脂餐后胆囊达最大收缩时残余容积（ＲＧＶ），（３）胆囊最大排空率（ＭＧＥＲ），（４）达最大收缩的经历时间。结果显示，ＩＢＳ患者的ＦＧＶ、达最大收缩时ＲＧＶ及经历时间均显著大于对照组（均为Ｐ＜０．０１），而其ＭＧＥＲ则显著小于对照组（Ｐ＜０．０１）．提示ＩＢＳ患者的胆囊收缩功能显著异常。

The authors studied gallbladder contraction in response to a meal,using ultrasonography in irritable bowel syndrome patients (n=15) and healthy controls(n=10). The following parameters were determined∶1) fasting gallbladder volume(FGV),2) residual gallbladder volume (RGV) after maximal contraction,3) maximum percent of gallbladder emptied(MGER), and 4) the time taken for maximal contraction. FGV and RGV after maximal contraction were significantly higher in the patient group,compared with controls (either P<0.01). The MGER was less and the time taken for maximal contraction was longer in the patient group than in the controls (either P<0. 01). Based on these observations, we conclude that patients with irritable bowel syndrome have significant abnormalities of gallbladder contractive function.