食管癌单纯放疗近期死亡病例分析

Analysis of risk factors of short-term death of patients with esophageal carcinoma treated with radiotherapy.

目的 探讨影响食管癌近期预后的因素。方法 回顾性分析225例食管癌行单纯6。Co外照射后一年内死亡病例的临床资料。结果 一年内死亡率为44．29％（225例）；年龄大于69岁死亡率55．56％（35例）；胸下段食管癌死亡率5.36％（62例）；病灶长度大于8．9cm死亡率54．02％（47例）；有远处转移者死亡率55．00％（44例）；放疗剂量在DT60-69Gy范围之外者死亡率达58.00％。结论 病灶部位愈低，病变长度愈长，死亡率愈高；年龄超过69岁者，有远处转移者死亡较高；放疗剂量以DT60-69Gy为宜；死亡率与性别、照射野数（P〉0．05）无关。

Objective To analyze the prognostic factors of patients with esophageal carcinoma treated with radiotherapy, Methods From Jan 1995 to May 1995, 508 patients with esophageal carcinoma were treated with radiotherapy alone. 225 patients died within one year after treatment, clinical data of these patients were retrospectively analysed. Results The one year overall mortality was 44. 3% （225/508 patients）, The mortality of patients older than 69 years was 55.56% （35 patients） ; The mortality of patients with carcinoma located in the lower part of the esophagus was 56.36% （62 patients） ; The mortality of patients with tumor longer than 8.9 em was 54.02% （47 patients） ; The mortality of patients with distant metastases was 55,00% （44 patients）. The mortality of patients received a total exposure dose greater than 60 -69Gy was 58.00%. Conclusion The lower the location of the tumor is or the longer the tumor is, the higher the mortality is. Patients older than 69 years or with distant metastases have a higher mortality. Exposure dose should be in the range of 60 -69Gy. Sex, pathologic classification and ,number of exposure fields do not affect the mortality.