摘要
目的:建立毒性中药生川乌的液质联用等质量检验方法。方法:采用显微、化学、液相色谱、液质联用方法进行定性鉴别、含量测定。结果:采用液相色谱质谱/质谱联用具有灵敏、专属性强等优点,适用于微量乌头生物碱的检测。结论:建立的方法可为其质量标准的提高提供参考。
AIM： Radix Aconite is unprocessed parent root tuber of Aconitum carmichaeli Debx. containing toxic diterpenoid alkaloids such as mesaconitine, aconitine and hypaconitine. To establish the quality standard for this portent herb. METHODS： The microscopic examination technique, HPLC-UV and LC-MS-MS methods had been used. RESULTS： These methods can be used to analyse the quality of this potent herb. CONCLUSION： This paper proposes microscopic examination technique and physio-chemical methods such as HPLC-UV and LC- MS-MS for the identification and quantitative analysis of the herbs.
出处
《中成药》
CAS
CSCD
北大核心
2006年第5期651-655,共5页
Chinese Traditional Patent Medicine
关键词
生川乌
液质联用
毒性
Aconitum carmichaeli Debx
diterpenoid alkaloids
HPLC
LC-MS-MS
