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白癜风患者血清相关细胞因子的检测 被引量：18

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摘要 探讨白癜风患者相关细胞因子的关系及在不同分型、分期中的作用,采用ELISA法分别测定白癜风患者血清γ-干扰素(IFN-γ)、白介素(IL)-4、IL-10、IL-12、肿瘤坏死因子(TNF)-α水平,并与正常对照组相比较。结果白癜风患者血清IL-4、IFN-γ、TNF-α水平增高,IL-2、IL-10水平降低,提示各种细胞因子可能参与白癜风发病,并与白癜风的活动有关。
作者 隋连金 戎丽娟 王炜
机构地区 山东省临沂市皮肤病医院
出处 《中国麻风皮肤病杂志》 2006年第5期386-388,共3页 China Journal of Leprosy and Skin Diseases
关键词 白癜风 Γ-干扰素 白细胞介素 肿瘤坏死因子-Α
分类号 R758.41 [医药卫生—皮肤病学与性病学]
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参考文献8

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二级参考文献27

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  • 8Morelli JG, Norris DA. Influence of inflammatory mediators and cytokines on human melanocyte function. J Invest Dermatol, 1993, 100(2Suppl) : S191 - S195.
  • 9Das L, Datta N, Bandyopadhyay S, et al. Successful therapy of lethal murine visceral leishmaniasis with cystatin involves up-regulation of nitric oxide and a favorable T cell response. J Immunol, 2001, 166(6) :4020 - 4028.
  • 10Tarrant TK, Silver PB, Wahlsten JL, et al. Interleukin 12 protects from a T helper type 1 - mediated autoimmune disease, exiperimental autoimmune uveitis, through a mechanism involving interferon gamma,nitric oxide, and apoptosis. J Exp Med, 1999, 189(2) :219 -230.

共引文献801

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引证文献18

二级引证文献115

中国麻风皮肤病杂志
2006年 第5期

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