304例非手术食管癌T分期与生存期相关性分析

The Relationship between CT T-Staging Criteria and Survival Time in 304 Cases Esophageal Cancer Treated with Nonoperative Methods

目的:探讨非手术治疗食管癌T分期与生存期的相关性。方法:对304例非手术治疗食管癌CT资料按照改良T分期标准进行分期。采用Wilcoxon检验分析T分期与生存期关系。结果:T1、T2、T3、T4中位生存期分别为53.0个月、30.6个月、17.5个月、15.7个月;经统计学检验,T1:T3,P=0.036,T1:T4,P=0.029;T2:T3,P=0.006,T2:T4,P=0.001,T1、T2期组生存率与T3、T4组比较有非常显著性差异,但T1与T2、T3与T4两两比较,T1:T2,P=0.289,T3:T4,P=0.438,无显著性差异。结论:T分期对评价及判断非手术食管癌预后有重要的临床价值,T3、T4期食管癌生存期明显较T1、T2缩短。

Objective： To evaluate the relationship between CT T-staging criteria and survival time in esophagus carcinoma treated by nonoperative therapy. Methods： The CT scan data of 304 patients were retrospectively analyzed according to CT-modified T-staging criteria, T1 5 cases, T： 49 cases, T3 127cases and T4 123 cases. All patients were followed-up after 1 year, 3 years and 5 years, respectively. Results： The mean survival time of T1、 T2、T3、 T4was 53.0, 30.6, 17.5 and 15.7 months, respectively. The data were analyzed using Wilcoxon methods, T1： T3, P=0.036, T1： T4, P=0.029; T2： T3, P= 0.006, T2： T4, P=0.001, all had significant difference, but T1： T2,P=0.289, T3： T4, P=0.438, without significant difference. Conclusion： CT T staging criteria of esophageal carcinoma is a very useful modality in evaluation prognosis of no-operation therapy esophagus carcinoma.