磨痂术配合生物敷料A在四肢深II度烧伤中的应用

Clinical evaluation of eschar grinding and biological dressing A for treatment of deep partial-thickness burn wound on the extremities

目的探讨磨痂术配合生物敷料A治疗四肢深II度烧伤的临床效果。方法将73例四肢深II度烧伤患者按创面处理方式分组,32例为磨痂术配合生物敷料A治疗组,41例为传统治疗对照组,观察两组病人的白细胞计数、体温、创面感染及愈合时间等。结果磨痂组与对照组比较,磨痂术配合生物敷料A处理创面可明显提高四肢深II度烧伤有效率(29/32vs31/41,P<0.05),全身炎症反应轻,创面愈合时间缩短(13.79±5.72vs17.08±8.39,P<0.01),瘢痕增生不明显。结论磨痂术配合生物敷料A是治疗四肢深II度烧伤创面较理想的方法,早期进行更佳,但对手部偏深的深II度烧伤仍不能完全替代早期削痂植皮术。

Objective To evaluate the clinical effect of eschar grinding and wound coverage by biological dressing A in the management of deep partial-thickness bum wound on the extremities. Methods Seventy-three patients with deep partialthickness bums on the extremities were divided into two groups to receive different managements. The patients in group 1 were treated with eschar grinding and wound coverage with biological dressing A, and group 2 received conventional treatment. The white blood cell count, body temperature, incidence of wound infection and wound healing time were observed. Results Compared with conventional treatment, wound management with eschar grinding and coverage by biological dressing A could increase the effective rate （29/32 vs 31/41, P〈0.05）, inhibit systemic inflammation and scar hypertrophy, and shorten the wound healing time （13.79±5.72 va 17.08±8.39, P〈0.01）. Conclusion Eschar grinding and wound coverage by biological dressing A can be effective for management of deep partial-thickness bums on the extremities, and earlier treatment with the dressing A achieves better effect.