期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

肿瘤坏死因子α基因多态性与精神分裂症 被引量：4

下载PDF
导出
摘要 近来研究表明异常的免疫功能在精神分裂症的发病中起了重要的作用。提示肿瘤坏死因子α(TNFα)基因可能是精神分裂症的易感基因,本文就TNFα基因多态性与精神分裂症的相关性进行综述。
作者 杨琴 司天梅 舒良
机构地区 北京大学精神卫生研究所
出处 《国际精神病学杂志》 2006年第2期77-80,共4页 Journal Of International Psychiatry
关键词 肿瘤坏死因子A 精神分裂症 基因多态性
分类号 R749.3 [医药卫生—神经病学与精神病学]
  • 相关文献

参考文献15

  • 1Gihnore JH, Jarskog LF, Exposure to infection and brain development: Cytokines in the pathogenesis of schizophrenia.Schizophrenia Research, 1997 ; 24: 365-367.
  • 2Loddick SA, Rothwel NJ. Mechanisms of tumor necrosis factor alpha action on neurodegeneration: interaction with insulin-like growth factor- 1. Proceeding of the National Academy of Sciences of the United States of America. 1999; 96: 9449-9451.
  • 3Kowalski J, Blada P, Kucia K, et al Neurolepties normalize increased release of interleukin-1 beta anti tumor necrosis factoralpha from monocytes in schizophrenia. Schizophr Res. 2001 ;50: 169-175.
  • 4Wilson AG, di Giovine FS, Blakemore AI, et al. Single base polymorphism in the human tumour necrosis factor alpha (TNF alpha) gene detectable by Nco I restriction of PCR product.Hum Mol Genet. 1992; 1: 353.
  • 5Louis E, Franchimont D, Piron A, et al. Tumor necrosis factor (TNF) gene polymorphism influences TNF-alpha production in lipolysaccharide (UXS) -stimulated whole blood cell culture in healthy humans. Clin Exp lmmunol. 1998; 113: 401-406.
  • 6Boin F, Zanardini R, pioli R, et al. Association btween-G308A tumor necrosis factor alpha gene polymorphism and schizophrenia. Mol Psychiatry, 2001; 6: 79-82.
  • 7Tan EC, Chong SA, Tan CH, et al. Tumor hecrosis factoralpha gene promoter polymorphisms in chronic schizophrenia.Biol Psychiatry, 2003; 54:1205-1211.
  • 8Meira-Lima Ⅳ, Pereira AC, Mota GF, et al, Analysis of a polymorphism in the promoter region of the tumor necrosis factor alpha gene in schizophrenia and bipolar disorder: further support for an association with schizophrenia. Mol Psychiatry,2003; 8: 718-720.
  • 9Schwab SG, Mondabon S, Knapp M, et al. Association of tumor necrosis factor alpha gene. G308A polymorphism with schizophrenia. Schizophr Res. 2003, 65: 19-25.
  • 10杨建中,司天梅,凌炎苏,阮燕,韩永华,王希林,周沫,张鸿燕,孔庆梅,李雪倪,刘萃,张大荣,舒良,张岱.肿瘤坏死因子α基因(TNFα)-G308A多态性与精神分裂症的关联[J].中国心理卫生杂志,2003,17(6):415-417. 被引量：12

二级参考文献21

  • 1Kendler KS. The genetics of schizophrenia : an overview. In: Tsuang MT, Simpson JC (Eds) .Handbook of Schizophrenia, Volume 3, Nosology, Epidemiology and Genetics of Schizophrenia. Amsterdam.Elsevier, 1988, 437 - 462.
  • 2Ganguli R, Yang Z, Shurin G, et al. Serum interlukin - 6 concentration in schizophrenia: elevation associated with duration of illness. Psychiatry Research. 1994, 51, 1 - 10.
  • 3Mcallister CGV, Kammen DP, Kelley ME.Relapse prediction in schizophrenia : from monoamines to cytokines. In: Ebert D, et al(Series Eds) .Advances in Biological Psychiatry, volume 18. In:Henneberg AE, Kaschka WP (Eds) . Immunological Alterations in Psychiatric Diseases. Basel. Karger, 1997, 44 - 49.
  • 4Hopkins S.I, Rothwell N.I. Cytokines and the nervous system I:Expression and regulation.Trends in Neuroscience. 1995, 18, 83- 88.
  • 5Mehler MF, Kessler JA. Hematolymphopoetic and inflammatory cytokines in neural development. Trends in Neurescience, 1997, 20,357 - 365.
  • 6Merrill JE. Tumor necrosis factor alpha, interleukin 1 and related cytokines in brain development: Normal and pathological. Developmental of Neuroscience, 1992, 14, 1-10.
  • 7Vitkovic L, Bockaert J, Jacque C. "Inflammatory" cytokines:Neuromodulators in normal brain? Journal of Neurochemistry.2000, 74, 457-471.
  • 8Gilmore JH, Jarskog LF. Exposure to infection and brain development: Cytokines in the pathogenesis of schizophrenia. Schizophrenia Research, 1997, 24, 365-367.
  • 9Bothwell NJ, Hopkins SJ. Cytokines and the nervous system Ⅱ:Action and nechanisms of action.trends in Neuroscienee, 1995,18, 130- 136.
  • 10Loddick SA. Rothwel NJ. Mechanisms of tumor necrosis factor alpha action on neurodegeneration: interaction with insulin - like growth factor - 1. Proceeding of the National Academy of Sciences of the United States of America, 1999, 96, 9449 - 9451.

共引文献11

同被引文献40

  • 1Kowalski J, Blada P, Kucia K, et al. Neuroleptics normalize increased release of interleukin-1 beta and tumor necrosis factor-alpha from monocytes in schizophrenia[ J ]. Schizophr Res, 2001, 50 ( 3 ) : 169-175.
  • 2Monteleone P, Fabrazzo M, Tortorella A, et al. Plasma levels of interleukin-6 and tumor necrosis factor alpha in chronic schizophrenia : effects of clozapine treatment[J]. Psychiatry Res, 1997, 71 ( 1 ) : 11- 17.
  • 3Theodoropoulou S, Spanakos G, Baxevanis CN, et al. Cytokine serum levels, autologous mixed lymphocyte reaction and surface marker analysis in never medicated and chronically medicated schizophrenic patients[J]. Schizophr Res, 2001, 47( 1 ) : 13-25.
  • 4Boin F, Zanardini R, Pioli R, et al. Association between-G308A tumor necrosis factor alpha gene polymorphism and schizophrenia [ J ]. Mol Psychiatry, 2001, 6(1): 79-82.
  • 5Czerski PM, Rybakowski F, Kapelski P, et al. Association of tumor necrosis factor-308G/A promoter polymorphism with schizophrenia and bipolar affeetive disorder in a Polish population [ J ]. Neuropsy- chobiology ,2008,57 ( 1-2 ) : 88-94.
  • 6Duan S, Xu Y, Chen W, et al. No association between the promoter variants of tumor necrosis factor alpha (TNF-alpha) and schizophrenia in Chinese Han population [ J ]. Neurosci Lett, 2004, 366 (2) : 139- 143.
  • 7Hanninen K, Katila H, Rontu R, et al. Tumor necrosis factor-alpha-G308A polymorphism in schizophrenia in a Finnish population[ J]. Neurosci Lett, 2005, 385 (1) : 76-81.
  • 8Hashimoto R, Yoshida M, Ozaki N, et al. Association analysis of the -308G > A promoter polymorphism of the tumor necrosis factor alpha (TNF-alpha) gene in Japanese patients with schizophrenia [ J ]. J Neural Transm, 2004, 111(2): 217-221.
  • 9Kampman O, Anttila S, Illi A, et al. Interaction of tumor necrosis alpha-G308A and epidermal growth factor gene polymorphisms in early-onset schizo- phrenia [ J ]. Eur Arch Psychiatry Clin Neurosci, 2005, 255(4) : 279-283.
  • 10Pae CU, Chae JH, Bahk WM, et al. Tumor necrosis factor-alpha gene polymorphism at position -308 and schizophrenia in the Korean population [ J ]. Psychiatry Clin Neurosci,2003, 57 (4) : 399-403.

引证文献4

二级引证文献8

国际精神病学杂志
2006年 第2期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部