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强迫症与多巴胺能作用 被引量：3

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摘要 本文综述了强迫症多巴胺能作用的动物模型、遗传多态性、脑神经影像学和神经生化、神经药理等方面的证据。
作者 苏中华 成义仁
机构地区 济宁医学院附属第二医院
出处 《国际精神病学杂志》 2006年第2期116-119,共4页 Journal Of International Psychiatry
关键词 强迫症 多巴胺 病理生理机制
分类号 R749.4 [医药卫生—神经病学与精神病学]
  • 相关文献

参考文献14

  • 1Blier P, de Montigny C. Possible serotonergic mechanisms underlying the antidepressant and anti-obsessive-compulsive disorder responses. Biol Psychiatry, 1998; 44(5): 313-323.
  • 2Campbell KM, McGrath MJ, Burton FH. Differential response of cortical-limbic neuropotentiated compulsive mice to dopamine D1 and D2 receptor antagonists. Eur J Pharmacol. 1999; 371(2-3): 103-111.
  • 3Sullivan RM, Eckert M J, Tse WS, et al. Effects of quinpirole on central dopamine systems in sensitized and non-sensitized rats. Neuroscience, 1998; 83(3):781-789.
  • 4Joel D, Doljansky J. Selective alleviation of compulsive leverpressing in rats by D(1), but not D(2), blockade: possible implications for the involvement of D(1) receptors in obsessivecompulsive disorder. Neuropsychopharmacology, 2003;28(1) : 77-85.
  • 5Little KY, Zhang L, Desmond T, et al. Striatal dopaminergic abnormalities in human cocaine users. Am J Psychiatry, 1999;156(2) : 238-245.
  • 6Metion O, Yazici K, Tot S, et al. Amisulpiride augmentation in treatment resistant obsessive-compulsive disorder, J Clin Psychopharmacol. 2003; 18(4): 463-467.
  • 7喻东山.强迫症治疗的新进展[J].中华精神科杂志,2005,38(1):50-52. 被引量：65
  • 8Ramasubbu R, Antiobsessional effect of risperidone add-on treatment in serotonin reuptake inhibitor-refractory obsessivecompulsive disorder may be dose-dependent. Arch Gen Psychiatry, 2002; 59(4): 472-473.
  • 9Van der Wee N, Stevens H, Harderman H, et al. Enhanced densities of dopamine but not of serotonin transporters in psychotropic-naive patients with obsessive-compulsive disorder. J Nucl Med. 2001; 42(2): 238.
  • 10Kim CH, Koo MS, Cheon KA, et al. Dopamine transporter density of basal ganglia assessed with [(123)I] IPT SPECT in obsessive-compulsive disorder. Eur J Nucl Med Mol Imaging,2003; 30(12) : 1637-1643.

二级参考文献14

  • 1Saxena S, Rauch SL. Functional neuroimaging and the neuroanatomy of obsessive-compulsive disorder. Psychiatr Clin North Am, 2000, 23:563-586.
  • 2Richelson E. Preclinical pharmacology of neuroleptics: focus on new generation compounds. J Clin Psychiatry, 1996, 57 Suppl 11:4-11.
  • 3Gabriels L, Cosyns P, Nuttin B, et al. Deep brain stimulation for treatment-refractory obsessive-compulsive disorder: psychopa-thological and neuropsychological outcome in three cases. Acta Psychiatr Scand, 2003, 107:275-282.
  • 4Flament MF, Bisserbe JC. Pharmacologic treatment of obsessive-compulsive disorder: comparative studies. J Clin Psychiatry, 1997, 58 Suppl 12:18-22.
  • 5Hollander E, Kaplan A, Allen A, et al. Pharmacotherapy for obsessive-compulsive disorder. Psychiatr Clin North Am, 2000, 23:643-656.
  • 6Gorman JM, Kent JM. SSRIs and SNRIs: broad spectrum of efficacy beyond major depression. J Clin Psychiatry, 1999, 60 Suppl 4:33-38.
  • 7Hollander E, Bienstock CA, Koran LM, et al. Refractory obsessive-compulsive disorder: state-of-the-art treatment. J Clin Psychiatry, 2002, 63 Suppl 6:20-29.
  • 8McDougle CJ. Update on pharmacologic management of OCD: agents and augmentation. J Clin Psychiatry, 1997, 58 Suppl 12:11-17.
  • 9Pigott TA. Gender differences in the epidemiology and treatment of anxiety disorders. J Clin Psychiatry, 1999, 60 Suppl 18:4-15.
  • 10Stein DJ. Advances in the neurobiology of obsessive-compulsive disorder:implications for conceptualizing putative obsessive-compulsive and spectrum disorders. Psychiatr Clin North Am, 2000, 23:545-562.

共引文献64

同被引文献29

引证文献3

二级引证文献5

国际精神病学杂志
2006年 第2期

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