摘要
目的:评价我院万古霉素应用的安全性。方法:对我院2005年5月~2005年11月应用万古霉素的50例患者的病原学检查、血药浓度监测、肾功能指标、合并用药及不良反应情况进行统计分析。结果:我院应用万古霉素基本安全。结论:注意监测血药浓度,实行个体化给药方案,及时纠正加重肾损害因素,将使万古霉素的应用更加安全。
OBJECTIVE: To evaluate the rationality of vancomysin use in the hospital where the authors work. METHODS: 50 patients taking vancomysin between May.2005 and Nov. 2005 were studied. The pathogenic examination,monitoring of drug concentration in blood, indices of renal function , combined use of drugs as well as adverse effects in these patients were reviewed and analyzed statistically. RESULTS: On the whole vancomysin use in our hospital was safe. CONCLUSION: Vancomysin use will be made safer by monitoring drug concentration in blood, individualizing drug administration, and timely correcting the aggravating factors of kidney injury.
出处
《中国药房》
CAS
CSCD
北大核心
2006年第10期757-758,共2页
China Pharmacy
关键词
万古霉素
血药浓度监测
肾功能
Vancomysin
Monitoring of drug concentration in blood
Renal function