ACNU经动脉内灌注治疗脑胶质瘤
摘要
作为手术治疗的辅助手段，化疗运用于脑胶质瘤治疗的历史由来已久，由于严重的毒副作用和化疗药物难以透过血一脑屏障等原因，长期以来一直未能得到广大医务人员的重视。随着对脑胶质瘤的病理生理发展规律过程的进一步加深、神经影像学的迅猛发展，特别是近年来亚硝脲类等一些可以通过血脑屏障的药物的开发，神经介入手段的日趋完备，采用介入方法经动脉行超选择化疗成为一种趋势，使人们重新对脑胶质瘤的化疗产生了浓厚的兴趣。
出处
《贵州医药》
CAS
2006年第3期281-283,共3页
Guizhou Medical Journal
参考文献17
-
1Yamada K,Ushio Y,Hayakawa T,et al.Quantitative au toradiographic measurements of blood-brain barrier permeability in the rat glioma model[J].J Neurosurg,1982,57(3):394-389.
-
2Roosen N,Kiwit JCW,Lins E,Schirmer M,Bock WJ.Adjuvant intraarterial chemotherapy with nimustine in the management og World Health Organization grade gliomas og the brain[J].Cancer,1989,64:1 984-1 994.
-
3Bamberg M.Budach V,Stuschke M,Gerhard L.Preliminary experimental results with the nitrosourea deriva tive ACNU in the treatment of malignant gliomas[J].Radiother Oncol,1988,12:25-29.
-
4Greenberg HS,Ensminger WD,Chandler WF,et al.Intra-arterial BCNU chemotherapy for treatment of malignant gliomas of the central nervous system[J].Neurosurg,1984,61:423-429.
-
5Yamada K,Ushio Y,Hayakawa T,et al.Distribution of radiolabeled 1-(4-amino-2-methyl-5-pyrimidinyl) methyl-3-(2-chloroethyl)-3-nitrosourea hydrochloride in rat brain tumor:intraarterial versus intravenous administration[J].Cancer Res,1987,47 (8):2 123-2 128.
-
6Miyagari M,Namba H,Saegusa T,et al.Intra-arterial mannital infusion in the chemotherapy for malignant brain tumors[J].Neurooncal,1993,15(2):185-193.
-
7L.Papavero,F.Loew,H.Jaksche.Intracarotid infusion of ACNU and BCNU as adjuvant therapy of malignant gliomas[J].Acta Neurochir(Wien),1987,85:128-137.
-
8Tomokatsu Hori,M.D.,Kiyoaki Muraoka,M.D.,Yoshikazu Satto,M.D.,et al.Influence of modes of ACNU administration on tissue and blood drug concentration in malignant brain tumors[J].Neurosurg,1987,66:372-378.
-
9Levin VA,Kabra PM,Freeman-Dove MA.Pharmacokinetics of intracarotid artery 14 C-BCNU in the squirrel monkey[J].Neurosurg,1978,48(4):587-593.
-
10Lutz RJ,Dedrick RL,Boretos.JW,et al.Mixing studies during intracarotid artery infusions in an in vitro model[J].Neurosurg,1986 Feb,64(2):277-283.
-
1张宏,段传志,李铁林,汪求精.动脉超选择化疗治疗颅内恶性肿瘤25例[J].实用医学杂志,2000,16(7):544-545.
-
2桂淑珍,彭小琴.脑胶质瘤超选择化疗的护理[J].实用临床医学（江西）,2004,5(4):151-151.
-
3胡晓林,缪仲荣.经动脉内超选择化疗脑胶质瘤并发症探讨[J].实用心脑肺血管病杂志,2001,9(4):226-227.
-
4徐士斌,朱钧,周耀,朱广军.超选择化疗栓塞在治疗原发性肝癌中的应用[J].中国交通医学杂志,2006,20(1):40-41. 被引量：2
-
5牟廷刚,赖良,谢飞,向鑫,徐波.TACE联合CT引导RFA治疗肝癌疗效评价[J].中国普通外科杂志,2014,23(7):996-999. 被引量：12
-
6吴永娟,唐光才,李玉伟.肝癌介入治疗的研究进展[J].医学综述,2007,13(3):235-237. 被引量：5
-
7郑丽平,初晓燕.肝动脉栓塞化疗术62例的护理[J].中国误诊学杂志,2011,11(32):8028-8028. 被引量：3
-
8顾泳.中晚期肝癌患者综合介入治疗一年生存率达74．1％[J].老年健康,2008(11):4-4.
-
9秦晓松,田应选.肺癌预后研究进展[J].实用医技杂志,2006,13(18):3310-3311. 被引量：1
-
10魏少贤.替莫唑胺联合放疗用于恶性脑胶质瘤患者的临床观察[J].临床医药文献电子杂志,2015,2(33):6785-6786. 被引量：2
