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在长春花细胞悬浮培养中细胞分裂素和乙烯通过甲基赤藓醇磷酸盐或萜类途径调控吲哚生物碱的产生 被引量:2

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摘要 长春花Catharanthus roseus(L)G.Don中的萜吲哚生物碱(TIAs)共同的母体化合物是异胡豆苷(strictosidine),而异胡豆苷由色胺和断马钱子苷(secologanin)立体定向缩合而成。由色氨酸脱羧酶(TDC)形成的1-色氨酸经过脱羧形成色胺;而断马钱子苷通过萜类途径由异戊烯基二磷酸(IPP)衍生而来。在IPP存在情况下,TIA主要是通过(选择的)甲基赤藓醇磷酸盐(MEP)途径,在质体中合成,而不是通过经典的甲羟戊酸途径在胞液中合成。作者研究了在长春花细胞悬浮培养中MEP和乙烯对TIA合成的调节作用。
出处 《国外医药(植物药分册)》 2006年第3期130-131,共2页
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  • 1张向飞,张荣涛,曹岚,王勇,王宁宁,王淑芳.不同因子对长春花愈伤组织中药用成分积累的影响[J].中国药学杂志,2004,39(11):817-819. 被引量:19
  • 2徐茂军,董菊芳.哺乳动物Bax基因在长春花细胞中的诱导表达及其对长春花生物碱合成的促进作用[J].中国科学(C辑),2006,36(6):500-507. 被引量:6
  • 3Dong-Hui Liu,Hong-Bin Jin,Yu-Hui Chen,Li-Jie Cui,Wei-Wei Ren,Yi-Fu Gong,Ke-Xuan Tang.Terpenoid Indole Alkaloids Biosynthesis and Metabolic Engineering in Catharanthus roseus[J].Journal of Integrative Plant Biology,2007,49(7):961-974. 被引量:7
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