摘要
以4-乙酰氨基环己醇为原料、Jones试剂作氧化剂合成了医药中间体4-乙酰氨基环己酮,反应条件温和、易于控制,反应时间大大缩短,收率稳定,效果令人满意。
Using Jones reagent as oxidant and 4-acetamidocyclohexanol as raw material,the medicinal intermediate N-(4-oxocyclohexyl) acetamid was synthesized. The experimental results showed: the reaction conditions were mild and controllable,the reaction time was shortened greatly while the yield was stable. Jones reagent was proved to be a satisfactory oxidant for the synthetic reaction.
出处
《化学与生物工程》
CAS
2006年第5期15-16,共2页
Chemistry & Bioengineering
基金
湖北省科技攻关计划项目(2005AA101C58)