自然流产妇女血清MDA、SOD、VitE的测定及意义

The determination of the level of maternal serum SOD,MDA and VE in patients with spontaneous abortion

目的:通过对自然流产妇女血清氧化应激指标———超氧化物歧化酶(SOD)、丙二醛(MDA)及维生素E(V itE)的测定,分析三个指标在自然流产发病机制中的意义。方法:用化学比色法对30例自然流产妇女及20例正常早孕组妇女血清中SOD、MDA及V it E进行测定。结果:与正常早孕妇女相比,自然流产妇女血清中MDA水平升高(P<0.05),SOD、V it E水平却下降(均P<0.05)。结论:上述三个指标对于预防及治疗自然流产有重要意义。

Objective： To determine the level of maternal serum SOD, MDA and VE in patients with spontaneous abortion in order to analyze their significance of pathogenesis of spontaneous abortion. Methods ： The levels of maternal serum SOD, MDA and VE was measured in 30 patients with spontaneous abortion and 20 normal early pregnant women by chemicalorimetry. Results： The level of maternal serum MDA in patients with spontaneous abortion was higher than that of normal early pregnant women （ P 〈0. 05 ） , while the levels of SOD and VE were significantly decreased （P 〈 0. 05, P 〈 0. 05） . Conclusion： The three indexes have more significance to treatment and prediction of spontaneous abortion.