摘要
目的:探讨复发性流产(RSA)与T淋巴细胞免疫功能的关系。方法:采用流式细胞仪与免疫荧光技术相结合,对20例RSA患者和16例正常早孕妇女蜕膜中T淋巴细胞及其亚群进行检测。结果:与对照组相比,RSA组患者蜕膜中总T淋巴细胞及CD4+T淋巴细胞百分率均升高(P(0.05),CD8+T淋巴细胞变化无显著性(P(0.05)。结论:蜕膜中T淋巴细胞亚群失衡可导致复发性流产。
Objective: To determine the relationship between occurrence of recurrent spontaneous abortion (RSA) and immune function of T - lymphoeytes and subsets. Methods: T - lymphocytes and subsets in deeiduas of 20 cases with RSA and 16 normal early pregnant women were detected by flow eytometry. Results: The percentage of CD3+ T ceils and CD4^+ T cells in deciduas of RSA patients was higher than that in the controls ( P 〈 0.05), CD8+ T cells had no difference between two groups ( P 〉 0.05 ) . Conclusion: The imbalance of T - lymphocyte subsets in deciduas are associated with RSA.
出处
《中国妇幼保健》
CAS
北大核心
2006年第10期1405-1406,共2页
Maternal and Child Health Care of China
关键词
流产
复发性
蜕膜
T淋巴细胞亚群
流式细胞术
Recurrent spontaneous abortion
Decidua
T- lymphocyte subsets
Flow cytometry