睡眠呼吸暂停综合征116例临床特点与年龄及肥胖的相关性分析

Correlation of sleep apnea syndrome with the age and body weight:A report of 116 cases

目的：探讨睡眠呼吸暂停综合征（sleep apnea syndrome，SAS）患者的临床特点与年龄及肥胖的相关性。方法：采用多导睡眠监测仪（PSG）对116例SAS患者进行睡眠监测，按体重指数（BMI）分为肥胖组（57例）与非肥胖组（59例），按年龄分为老年组（26例）与中青年组（90例），分析对应组间SAS患者的临床特点。结果：呼吸暂停低通气指数（AHI）、最长呼吸暂停持续时间（LAT）、平均呼吸暂停持续时间（MAT）肥胖组较非肥胖组高，最低血氧饱和度（LSaO2）、平均血氧饱和度（MSaO2）肥胖组较非肥胖组低，差异均有显著性（P〈0．005-P〈0．001）。颈围、BMI老年组较中青年组低，差异均有显著性（P〈0．01-P〈0．005）；AHI、LAT老年组较中青年组低，ISaO2、MSaO2老年组较中青年组高，差异均有显著性（P〈0．05～P〈0．005）。结论：肥胖组SAS患者严重程度较非肥胖组SAS患者重，老年组SAS患者严重程度较中青年组SAS患者轻．

Objective ：To investigate the correlation between sleep apnea syndrome （SAS） and the age and body weight. Methods： One hundred and sixteen patients with SAS were diagnosed by polysomnography（PSG） and classified into the aged group and middleaged group, the obesity group and non-obesity group. Results ：The apnea hypopnea index（AHI） , longest apnea time （LAT） and mean apnea time（MAT） of the obesity group were significantly higher than those of the non-obesity group,and the index of lowest arterial O2 saturation（ LSaO2 ） and mean arterial O2 saturation（ MSaO2 ） were lower than those of the non-obesity group（ P 〈 0. 005 to P 〈 0.001 ）. Both the body mass index（BMI） and neck circumference were lower in the aged group than in the middle-aged group（ P 〈 0.01 to P 〈 0. 005） ; AHI, LAT and MAT were lower in the aged group comparatively. LSaO： and MSaO2 were significantly higher in the aged group than those in the middle-aged group （ P 〈 0.05 to P 〈 0. 005 ）. Conclusions： The severity of SAS is positively correlated with body weight and negatively correlated with age.