喉癌术后并发咽瘘的相关因素分析

Analysis of the predisposing factors of pharyngo-cutaneous fistulae following laryngeal cancer surgey

目的探讨喉癌术后咽瘘发生的相关因素。方法对115例喉癌患者术后可能并发咽瘘有关的临床资料进行统计分析。结果年龄≤60岁,病变T2或T3期,营养状况良好,术前未接受放疗,手术时间≤6h,手术方式为部分喉切除的喉癌患者术后并发咽瘘的发生率明显低于年龄>60岁,病变为T4期,营养较差,术前放疗,手术时间>6h,全喉切除的患者(P<0.05)。喉癌患者术后可能并发咽瘘与手术切口类型,术后引流方法无关。结论喉癌患者年龄、营养状况、肿瘤临床分期、手术方法、术前放疗、手术时间可能是术后并发咽瘘的主要影响因素。

Objective To search the predisposing factors of pharyngo-cutaneous fistulae after surgical treatment of laryngeal cancer. Methods The clinical datas related to pharyngo-cutaneous fistulae following laryngeal cancer surgey were analyzed statistically in 115 cases with laryngeal cancer. Results The incidence rate of phargngo-cutaneous fistrulae following laryngeal cancer surgey in laryngal cancer who were younger than 60,in T2 or stage, in good. nutrition, with out preoperative radiother apy. Whose operation time were below 6h,or taken partial laryngectomy,was significantly less than that of those who were over 60 years old,in T4 stage,in malnutrition,with preoperative radiotherapy,or whose operation time were over 6h,or taken total laryngectomy respectively. But didn＇t related to incision time and post surgical drainage. Conclusion preoperative,radiotherapy and operation time may play ing laryngeal cancer surgey. The age, nutrition conditions, clinical stage, operation type, an important role in the pharyngo-cutaneous fistulae following laryngeal cancer surgey.