肺源性心脏病泡内肺动脉图像形态定量分析

Image Morphological Quantitative Analysis of Intra-Acinar Pulmonary Arteries in Cor Pulmonale

应用图像分析仪测量了３３例肺心病尸检病例的泡内肺动脉的管腔面积／管总面积（ＥＡ／ＴＡ），管壁面积／管总面积（ＷＡ／ＴＡ）及管壁厚／管外径（ＷＤ／ＴＤ）３个相对比值。结果发现，尸检中由慢性支气管炎及弥漫性肺间质纤维化发展为肺心病者，与无肺心病者的泡内肺动脉相比，其ＥＡ／ＴＡ值均显著减少，而ＷＡ／ＴＡ及ＷＤ／ＴＤ值均显著增大，这对肺心病的定量病理诊断及探讨其发生发展均有一定的研究价值。

The relative ratios of vessel lumen area/total area (EA/TA),vessel wall area/total area (WA/TA)and vessel wall thickness/vessel external diameter (WD/TD) of intra-acinar pulmonary arteries obtained from 33 cases of cor pulmonale were calculated with image analysor.The results showed that compared with the intra-acinar pulmonary arteries in patient without cor pulmonale,the relative ratios.of EA/TA decreasd significantly,while values of WA/TA and WD/TD increased significantly in patients with cor pulmonale due to chronic bronchitis and pulmonary interstitial fibrosis.The results are of meaning for the quantitative pathological diagnosis and studying the development of the cor pulmonale.