灵芝片抗疲劳作用实验研究

Experimental research of glossy ganoderma pills on antifatigue effect

目的研究林中宝灵芝片抗疲劳的作用。方法按小鼠体重分为高、中、低剂量组。分别灌胃给予1.03、0.36、0.18g/kg的灵芝片30d,对照组给予生理盐水。通过小鼠负重游泳实验测定小鼠耐缺氧时间、小鼠肝糖原含量改变及小鼠血清尿素氮含量变化等。观察小鼠运动性疲劳时林中宝灵芝片对体内相关指标的影响及其机制。结果林中宝灵芝片组小鼠游泳时间、耐缺氧力、肝糖原含量、血清尿素氮含量降低均与生理盐水组有显著差异。结论林中宝灵芝片有明显的抗疲劳作用。

Objective To study the effect of Linzhongbao glossy ganoderma pills on antifatigue effect. Methods The mice were divided into the highest, median and lowest three groups by weight. 1.03, 0.36, 0.18 g/kg glossy ganoderma pills were by intragastric administration for 30 days separately with saline for control. The hypoxic tolerant time, content change of hepatic glycogen and serum urea nitrogen were determined through the weight loading swimming experiment. The change of the relative indexes in vivo was observed after glossy ganoderma pills used and its mechanism also was approached when the mice were in fatigue. Results Compared with control group, there was significant difference in the hypoxic tolerant time, content of heapatic glycogen and serum urea nitrogen in Linzhongbao glossy ganoderma pills groups. Conclusion Linzhongbao glossy ganoderma pills has obviously antifatigue effect.