化妆品性皮肤病341例临床分析

Clinical Analysis on 341 Cases of Cosmetic Dermatosis

为了了解化妆品性皮肤病状况,对341例化妆品性皮肤病进行了临床观察。并对部分患者做了可疑致病化妆品与仿欧标准抗原的斑贴试验。结果,中青年女性患者居多,临床表现主要为接触性皮炎(78.59%),其次是色素沉着(10.26%)、痤疮样损害(9.97%)、光感性皮炎(0.59%)、接触性荨麻疹(0.59%)。可疑致病化妆品种类141种,大部分是一股护肤品(63.83%)。215例做了可疑化妆品斑试,阳性率61.86%,以接触性皮炎型和色素沉着型阳性率较高(63.75%与80.65%)。仿欧标准抗原斑试结果显示化妆品中常见的致敏原是香料和防腐剂。

In order to study the characteristics of cosmetic dermatosis,unwanted effects of cosmet- ics in the 341 patients were observed,and some of them were patch tested with suspected cosmetics and antigens modelled after European Standard Series.Most patients were female,age ranged 18 to 45.Of them 268 (78.59%) were contact dermatitis,35 (10.26%) were hyperpigmentation,34 (9.97%) were ache-like lesions.One hundred and forty one kinds of cosmetics were suspected to be responsible for the dermatoses.Of these 141 cosmetics,63.83% belonged to skin care products.Two hundred and fifteen cases were patch tested with suspected cosmetics,among them 61.86% showed a positive result.The results of patch tests with antigens modelled after Europe Standard Series in patients with cosmetic der- matitis showed that the common allergens in cosmetics were fragrance and preservatives.