超声引导下深部淋巴结活检对恶性淋巴瘤诊断的临床分析

Percutaneous ultrasound-guided core needle biopsy in deep lymphonods for diagnosis of malignant lymphoma

目的:探讨超声引导下深部淋巴结活检穿刺小标本对恶性淋巴瘤诊断的临床价值。方法:采用超声引导下淋巴结穿刺活检,经石蜡包埋,HE染色及免疫组化标记的方法进行病理诊断与以往手术切除活检的标本进行比较。结果:31例住院治疗的深部淋巴结肿大患者,超声引导下穿刺标本,并对不同部位、类型的恶性淋巴瘤进行病理诊断及亚型分型,与以往手术切除淋巴结活检相比具有阳性率相同,创伤小,价格低廉,简便易行的特点。结论:超声定位下的淋巴结穿刺活检可以代替淋巴结切除活检,对于仅有深部淋巴结肿大的患者可作为诊断恶性淋巴瘤的方法。

Objective：To evaluate the effectiveness of percutaneous ultrasound （US）-guided core needle biopsy in deep lymphonods in diagnosing malignant lymphoma. Methods： Patients with malignant lymphoma underwent percutaneous US-guided core needle biopsy in deep lymphonods. The sample tissues were embedded in paraffin and stained with HE. Pathological diagnosis was made by immunohistochemical staining. The results were compared with that of surgical biopsy. Results： Specimens were obtained by US-guided biopsy from 31 inpatients with deep lymph node enlargement. Pathological diagnosis was made under microscope to determine the histological subtypes of different kinds of malignant lymphoma in different locations. Percutaneous US- guided core needle biopsy had the same positive predictive value with surgical biopsy and caused small lesions. It is a safe and easy procedure with lower cost in the diagnosis of malignant lymphoma. Conclusion：Percutaneous US-guided core needle biopsy was a valid alternative to surgical biopsy. It is a useful method in diagnosing malignant lymphoma for the patients who had only deep lymph node enlargement.