人白细胞α型干扰素治疗小儿传染性单核细胞增多症的观察

Curative Effect of Interfon-Alpha in Children with Infectious Mononucleosis

本文报道用人白细胞α型干扰素治疗传染性单核细胞增多症（ＩＭ）３１例。干扰素用量为１×１０７ｕ，每日肌注一次，连续５～７天。结果：干扰素治疗病例的热程、咽峡炎、淋巴结肿大、肝脾肿大持续时间均较非干扰素治疗组（２７例）明显缩短，其热程缩短１周左右。由此表明干扰素治疗ＩＭ可缩短疾病的病程，有抗ＥＢＶ活性。

hirty-one cases of infectiou mononu-cleosis treated with Interfon-Alpha were reported.The dose of intramuscular injection was one millionunits per day for 5-7 days. The recovery course of fev-er,anuina,lymphadenopathy and hepatosplenomegaly was much shorter in the study group than in the con-trol group(27 cases).The results suggested that in-terfon-Alpha should ha efficacious against EBV activi-ty and might shorten the course of this disease.