黄花远志根化学成分的分离和结构鉴定

STUDIES ON CHEMICAL CONSTITUENTS OF POLYGALA ARILLATA BUCH-HAM

从黄花远志（ＰｏｌｙｇａｌａａｒｉｌｌａｔａＢｕｃｈ－Ｈａｍ．）根中分离得到７个化合物，根据光谱（ＵＶ，ＩＲ，ＭＳ，￣１ＨＮＭＲ，ＤＩＦＮＯＥ和￣（１３）ＣＮＭＲ）解析和理化性质，分别鉴定为１－甲氧基－２，３－亚甲二氧基酮（Ｉ）、１，７－二羟基－２，３－亚甲二氧基酮（ＩＩ）、１，６，７－三羟基－２，３－二甲氧基酮（ＩＩＩ）、对羟基苯甲酸（ＩＶ）、远志醇（Ｖ）、豆甾醇（ＶＩ）、豆甾醇β－Ｄ－吡喃葡萄糖甙（ＶＩＩ）。其中，ＩＩ和ＩＩＩ为新化合物，ＶＩ和ＶＩＩ为旨次从该植物中分得。化合物Ｉ～ＩＩＩ有抑制醛糖酶的作用。

Seven compounds were isolated from the roots of Polyyala arillata Buch-Ham. Onbasis of chemical reactions and spectral (UV) IR ,MS,1 HNMR,DIFNoE,13CNMR)analysis, theywere identified as 1-methoxy-2,3-methylenedioxyxanthone(I),1,7-dihydroxy-2,3-methylene-dioxyxanthone(II),1,6,7-trihydroxy-2,3-dimethoxyxanthone(III),p-hydroxy-benzoic acid(IV),polygalitol(V),stigmasterol(VI)and stigmasterol-3-O-β-D-glucopyranoside(VII).II and IIIare new compounds.Pharmacological study indicated that I,Il and III inhibit aldose reductase.