氟草定乙酯的合成

Synthesis of fluroxypyr ethyl ester

采用3,5-二氯-2,6-二氟-4-氨基吡啶和α-羟基乙酸乙酯为原料,在氢化钠存在下,反应制备氟草定乙酯,收率70%。

4-Amino-3,5-dichloro-6-fluoro-2-pyridyloxy acetic acid ethyl ester was prepared by reaction of 4-amino- 3,5-dichloro-2,6-fluoro-2-pyridine with ethyl glycolate in the presence of sodium hydride. Product yield was 70%.