端粒、端粒酶与肿瘤诊治的研究进展

端粒酶已经成为当今最受重视的抗肿瘤治疗的新靶点之一，人们对于端粒及端粒酶的认识也在不断加深,端粒酶可作为肿瘤诊断和预后的一个重要生物标志，抑制端粒酶可能成为一种有发展前途的抗肿瘤措施。本文综述了端粒和端粒酶的构成和功能，“端粒-端粒酶”假说，端粒酶与肿瘤的关系。

Now, telomerase has been a diagnostic marker and a new therapeutic target for cancer.It could be an important sign which for tumor＇diagnosis and prognostic, Contral telomerase would be a useful measure to therapy tumor.This review summarized structure and function of telomere,telomerase, ＂telomere-telomerase＂hypothesis,telomerase＇s relation to cancer.