急性脑梗死动脉内接触性溶栓治疗的临床研究

Clinical study of intraartery thrombolytic therapy in acute cerebral infarction

目的 :观察急性脑梗死动脉内接触性溶栓治疗的临床效果及并发症 ,探讨溶栓的时间窗。方法 :对 2 5例发病在 12h内的急性脑梗死患者 ,先行全脑血管造影 (DSA)确定闭塞血管后 ,分别进行动脉内微导管接触性溶栓治疗。结果 :17例闭塞血管再通 ,再通率为 6 8.0 %。结论 :动脉内接触性溶栓治疗急性缺血性脑梗死是一种安全有效的方法 ,溶栓开始的时间与疗效及预后关系密切。

Objective To observe therapeutic effect and complication of the intraartery thrombolytic therapy in acute cerebral infarction,to investigate the time window of thrombolytic therapy. Methods 25 acute cerebral infarction cases within 12 hours had been treated. After finding the occlusive artery by DSA technique, the intraartery thrombolytic therapy wa＇s performed. Results Complete/partial recanalised in 17 patients,the re＇canalised rate just after infusion was 68%. Conclusion The intraartery thrombolytic therapy is efficient and safe method in the setting of acute cerebral infarction,the time of beginning thrombolysis is closely related with the efficacy and prognosis.