胃癌与七种元素关系的分析

Analysis of the Relation between Gastric Carcinoma and the 7 Elements

57例胃癌癌灶内锌值为(13.740±4.150)×10^(-6),低于癌边缘组织(15.677±4.567)×10^(-6)(P<0.01),亦低于正常组织(15.897±3.580)×10^(-6)(P<0.01)。癌灶铜值为(7.91±6.19)×10^(-6),高于正常组织(5.62±12.01)×10^(-6)(P<0.05),癌灶铜/锌比值亦高于正常组织(P<0.01),但与边缘组织无显著性差异。分化较好的胃腺癌与未分化癌间七种微量元素含量均无显著性差异。这些结果提示,胃癌组织中锌值的降低与铜/锌比值的升高可作为胃癌的辅助诊断指标,而且锌值的检测更具意义。但与分化程度无关。

In the 57 cases of gastric carcinoma, the Zn level in cancer loci was (13. 740±4. 150) × 10-6, that was lower than in its peripheral tissue (15.677±4. 567) ×10-6 (P<0. 01), and lower than in its normal tissue (15. 897±3. 580) ×10-6 (P<0. 01) . The Cu level was (7. 91 ±6.19) ×10-6in the cancer loci and higher than in its normal tissue (5.62±2. 01) ×10-66 ( P <0. 05) . The ratio of Cu/Zn in the cancer loci was higher than in its normal tissue, either, but had no significant difference with the peripheral tissue. There was no significant difference of contents of the 7 elements between high differented gastric adenocarcinoma and un-differented carcinoma. The results indicate that the reduce of the Zn level and the increase of the ratio of the Cu/Zn can be the supplementary diagnostic index of gastric carcinoma, and the determination of the Zn level is more important, but the Zn level has no relation with the differentiation.