奥曲肽治疗食道静脉曲张破裂出血

Curative Effect of Oetreotide in Treating Esophageal Varix Bleeding

目的验证对比奥曲肽治疗食道静脉曲张出血不同给药方式的止血效果。方法将28例经胃镜检查证实为食道静脉曲张破裂出血(EVB)的患者随机分为两组,一组持续静脉滴注,一组间断静脉推注或加壶,通过三腔管抽吸胃内容物观察止血效果,并记录患者的输血量及不良反应。结果6h以后的止血率:持续滴注组为71.4%,显著高于间断给药组(50%),输血量明显少于后者。不良反应虽有差别,但无统计学意义。结论在治疗EVB时奥曲肽持续静脉给药,优于间断给药。

Objective To explore the contrast of curative effects in curing esophageal varix bleeding（EVB） by utilizing oetreotide in different ways. Methods Divide 28 cases, who have been proved to suffer from esophageal varix bleeding due to the rupture of the blood vessel into two groups. One is treated by continuous intravenous drip;the other by discontinous pushing intravenous injection or by adding this medicine into the injection pot. Then observe the effect of stopping bleeding by drawing contents in the stomach through the tube with three cavities and two bags and write down the amount of blood transfusion and the bad reaction. Results group by continuous drip reaches 71.4% ,which 6 hours later, the rate of stopping bleeding of the is obviously higher than that（ which is 50% ）by discontinuous supply of the medicine ; at the same time the amount of blood transfusion is obviously less than that of the latter. The difference of the bad reacton exists but very faint. Conclusion In curing EVB,the continuous supply of the medicine is superior to the discontinuous supply.