摘要
AIM: To investigate the incidence of bacterial overgrowth in the stomach by using a new endoscopic method in which intragastric hydrogen and methane gases are collected and analyzed. METHODS: Studies were performed in 490 consecutive patients undergoing esophagogastroscopy, At endoscopy, we intubated the stomach without inflation by air, and 20 mL of intragastric gas was collected through the biopsy channel using a 30 mL syringe, Intragastric hydrogen and methane concentrations were immediately measured by gaschromatography, H pylori infection was also determined by serology. RESULTS: Most of intragastric hydrogen and methane levels were less than 15 ppm (parts per million). The median hydrogen and methane values (interquartile range) were 3 (1-8) ppm and 2 (1-5) ppm, respectively. The high hydrogen and methane levels for indication of fermentation were decided if the patient had the values more than 90 percentile range in each sample. When a patient had a high level of hydrogen or methane in one or more samples, the patient was considered to have fermentation. The overall incidence of intragastric fermentation was 15.4% (73/473), Intragastric methane levels were higher in the postoperative group than in other groups. None of the mean hydrogen or methane values was related to Hpylori infection. CONCLUSION: Hydrogen and methane gases are more frequently detected in the stomach than expected, regardless of the presence of abdominal symptoms. Previous gastric surgery influences on the growth of methaneproducing bacteria in the fasting stomach.
瞄准:由使用胃内氢和甲烷气体镇定、分析的一个新内视镜的在方法在胃调查细菌的增生的发生。方法:研究在经历食管胃镜检查的 490 个连续病人被执行。在内视镜检查法,我们把管子插进没有通货膨胀的胃坐飞机,并且胃内气体的 20 mL 用 30 mL 注射通过活体检视隧道被收集。胃内氢和甲烷集中被煤气的层析立即测量。H pylori 感染被血清学也决定。结果:大多数胃内氢和甲烷层次是不到 15 ppm (兆比率) 。中部的氢和甲烷价值(内部 quartile 范围) 是 3 (1-8 ) ppm 并且 2 (1-5 ) ppm 分别地。为发酵的指示的高氢和甲烷层次被决定病人是否有在各个的超过 90 百分位数范围取样的价值。当一个病人在至少一件样品有氢或甲烷的高水平时,病人被认为有发酵。胃内发酵的全面发生是 15.4%(73/473 ) 。胃内甲烷层次比在另外的组在手术后的组是更高的。任何一个吝啬的氢或甲烷价值都不与 H pylori 感染有关。结论:氢和甲烷气体是经常比期望在胃检测的更多,不管腹的症状的存在。对在禁食胃的生产甲烷的细菌的生长的以前的胃的外科影响。