摘要
目的 观察中老年妇女肥胖与血清性激素、血脂、自由基的关系,探讨中老年妇女肥胖的可能机制.方法调查对象为35～62岁的妇女,按体重指数（BMI）分为4组：（1）肥胖组,BMI≥28,（2）超重组,24≤BMI＜28,（3）正常组,18.5≤BMI＜24,（4）消瘦组,分别测定血脂、血清中雌二醇（E2）、卵泡刺激素（FSH）、催乳素（PRL）和血清中SOD、MDA、NO含量.结果肥胖和超重者分别占被调查的10.0%和32.8%,肥胖组中血脂（除APOA1）、E2、SOD、MDA、NO与正常组比较,均有显著性差异（P＜0.05）.结论中老年妇女肥胖可引起血脂增高,雌激素水平下降,自由基增多.
Objective To observe the relationship between estrogen, lipoid, free radical in serum and obesity in mid -elderly women. Methods The mid - elderly women were divided into 4 groups in BMI. group 1, obesity, group 2, overweight, group 3, normal, group 4, lowweight. They were determined by the level of E2, FSH, PRL, lipoid, SOD, MDA, NO in serum. Results The rate of obesity and overweight is respectively 10. 0%, 32. 8% in the mid - elderly women. There was significant difference of E2 , TC, TG, LDL- C, LDL, ApoB, ApoA1/ ApoB, SOD, MDA in serum between obesity groups and normal groups （P〈0. 05） . Conclusions Obesity may induce rise of level of lipoid, decline of estrogen, increase of free radical.
出处
《锦州医学院学报》
2006年第3期46-47,共2页
Journal of Jinzhou Medical College
关键词
肥胖
性激素
血脂
自由基
中老年妇女
obesity
estrogen
serum lipoid
free redieal
mid -elderly women
