从辨证论治的思维特征探索证候分类研究的比较参照体系

On Establishing Comparative Reference System for Syndrome Classification Study from the Thinking Characteristics of Syndrome Differentiation Dependent Therapy

从中医辨证论治的思维特征角度出发,通过分析辨证论治的思维过程,疾病、证候、方剂的基本特征,结合现代循证医学的基本原则以及病证结合动物模型的可行途径等方面,探讨建立证候分类研究的比较参照体系。围绕证候病机及其与疾病和方剂的相关性这一中医证候研究的重要科学问题,论述建立以“方剂”治疗效应为比较参照体系的可操作性。坚持突出中医学思维特征与现代科学设计融合的研究思路,以方剂干预治疗效果作为比较参照系统,基于中医以方测证的逆向思维的认“证”方法,不断积累、完善,由此建立具有坚实临床科学基础的证候标准,可能成为当前病证结合、证候研究的有效途径之一。

To create a comparative referential system for syndrome classification study by viewing from the thinking characteristics of TCM on syndrome differentiation dependent therapy （SDDT）, through analyzing the thinking process of SDDT, and the basic features of disease, syndrome and prescription, combining the basic principles of modern evidence-based medicine and feasibility of establishing integrative disease-syndrome animal model. The practice of creating a comparative referential system based on clinical efficacy of prescription was discussed around syndrome pathogenesis and its relationship with disease and prescription, which was one of the important scientific problems in TCM syndrome study. The authors hold that, it may be one of the available ap- proaches for the present study on integration of disease with syndrome by way of insisting on the thinking pathway of stressing the characteristics of TCM and intermerging with modern scientific design ; on taking the efficacy of prescription as the comparative reference system to accumulate and improve unceasingly according to the TCM method of syndrome diagnosis inferred from effect of prescription with reverse thought （i. e. to differentiate syndrome from the effect of prescription）, and thus build up the syndrome diagnostic standard on the solid clinical and scientific base.