我院2002年～2004年抗感染药物应用调查与细菌耐药性分析

An Analysis of the Use of Antiinfective Drugs and Bacterial Drug Resistance in Our Hospital During the Period 2002～2004

目的：了解我院抗感染药物临床使用情况.方法：以购入金额、日用药人次数、日均药费对我院2002年～2004年抗感染药物进行分类统计、综合分析.结果：3年来,我院抗感染药物购入金额逐呈增长.各亚类抗感染药物中头孢菌素类、喹诺酮类、青霉素类、抗真菌类购入金额排序依次占前4位,β-内酰胺酶抑制剂位序呈上升趋势,氨基糖苷类、磺胺类位序下调.用药频度前30位中,大多数是一线口服抗感染药.抗菌药物的细菌耐药率增长迅速.结论：我院临床抗感染药物使用基本合理,但仍需加强抗感染药物的合理应用和规范化管理,控制细菌耐药率再度增长.

OBJECTIVE：To investigate the current use of antiinfective drugs in our hospital during the period 2002 to 2004. METHODS： Antiinfcctive drugs used in our hospital from 2002 to 2004 were made classification statistic and comprehensive analysis by using the methods of amount of money of drug purchase , daily men - times of drug use and daily costs of drug consumption. RESULTS： Total amount of money of drug purchase of antiinfective drugs had increased with years since the last three years. Amount of money of drug purchase of cephalosporins,quinolones,penicillins and antifungals ranked in the first four places in turu. The order of β - lactamase inhibitors was rising , but that of aminoglycosides and sulfonamides was descendant. Of the drags which ranked in the first 30 places in DDDs, most antiinfective drugs were the first - line dn.gs for oral use. Bacterial drug resistance rates of antiinfectivc drugs were growing rapidly. CONCLUSION ： The use of antiinfective drugs in the clinic in our hospital is basically reasonable. However, rational use and standardized administration of antibiotic drugs still need to be strengthened, in order to control re - growing of bacterial drug resistance rate.