三黄洗剂对鼻内镜术后鼻腔黏膜恢复的影响

Therapeutic effect of irrigating to the operative cavity with Sanhuang Irrigating Solution on the recovery of nasal mucosa following endoscopic sinus surgery

目的探讨中药三黄洗剂盥洗术腔对鼻内镜术后疗效和鼻黏膜形态恢复过程的影响。方法因鼻息肉、鼻窦炎而接受鼻内镜手术的患者66例,随机分为两组,每组33例。两组患者均于鼻内镜术后予以常规处理,而治疗组则加用中药三黄洗剂盥洗术腔,对照组只用生理盐水盥洗术腔。随访半年,按海口1997内窥镜手术疗效评定标准进行疗效评估。结果治疗组鼻黏膜水肿消退和上皮化速度较对照组明显增快,两组差异具有显著性意义(P<0.05)。结论鼻内镜术后应用三黄洗剂盥洗术腔,有助于促进鼻黏膜形态的良性恢复。

Objective To investigate the effect of irrigating to the operative cavity with Sanhuang Iirrigating Solution （SIS） on the therapeutic effect of endoscopic sinus surgery （ESS） on chronic sinusitis and/or nasal polyps and on the recovering progress of nasal mucous membrane following the surgery. Methods Included in this study were sixty-six cases with chronic sinusitis and/or nasal polyps received ESS. They were randomly divided into two groups, with 33 cases in each. All the cases in the 2 groups were given routine treatment after the operation, with those in treating group （TG） treated additionally by irrigating the operative cavity with SIS and those in controlling one （CG） treated additionally by irrigating the operative cavity only with 0.9 % N.S. following the operation. Then, the therapeutic effect was evaluated under endoscope by the end of following up period last for 6 months and compared between the 2 groups, based on a standardized therapeutic effect evaluating system. Result The extinctive course of edema in nasal mucous was obviously shorter and the speed of epithelization in nasal mucosa was significantly higher in TG than that in CG, with a significant difference between them （P 〈 0.05）. Conclusions Irrigating to the operative cavity with SIS is very beneficial to the promotion of nasal mucosa recovering following endoscopic sinus surgery and can result in a better morphological recovery.