摘要
血凝素蛋白(HA)既是一种重要吸附蛋白,介导禽流感病毒吸附和穿入宿主细胞而发挥致病作用,也是一种良好的保护性抗原,对宿主抵抗禽流感起到了决定性保护作用。研究HA蛋白对揭示禽流感病毒的致病机理和免疫防治禽流感均具有重要意义。本文重点概述了HA蛋白的结构、功能和蛋白表达方面的研究进展,并对HA蛋白在禽流感疫苗中的应用进行了探讨。
Hemaglutinin (HA) is an important absorbent protein and effect.iv protective antigen of AIV. It not only mediates AIV to adsorb and penetrate cells, but also makes the host produce immunity against AIV. Studing HA have a vital significance to reveal pathogenic mechanism of AIV and immunoprevention AI. This article reviewed structure, biological function and expression of HA. The application of HA in AI vaccine was also discussed.
出处
《现代生物医学进展》
CAS
2006年第4期61-62,72,共3页
Progress in Modern Biomedicine
基金
省科技攻关项目
关键词
禽流感病毒
血凝素蛋白
结构
功能
表达
avian influenza virus(AIV)
hemagglutinin (HA)
structure
biological function
expression