快速减重对人体血液流变学特性的影响

Effect of Rapid Body Weight Loss on Hemorheology

目的:通过观察快速减重前后的血液流变学各项指标的变化,探讨快速减重对血液流变学特性的影响。方法:测定受试者正常水合(0%BWL)、桑拿或运动脱水快速减重2%(2%BWL)、4%(4%BWL)3种不同状态下的血液流变性的指标,观察全血粘度(高、中、低切)、血浆粘度(PV)、红细胞压积(Hct%)、红细胞变形指数(TK)、红细胞刚性指数(VR)、红细胞聚集指数(A1、A2)等指标的动态数值。结果:(1)2%BWL和4%BWL时全血粘度(高、中、低切)、血浆粘度、红细胞压积、纤维蛋白原(Fi)、TK、VR、A1、A2明显升高(P﹤0.05);(2)4%BWL时血液流变学各指标变化明显高于2%BWL(P﹤0.05);(3)桑拿快速脱水组与运动快速脱水组的血液流变学各指标在同等程度脱水程度下相比较,有差异,但差异没有统计学意义(P>0.05)。结论:快速减重可引起血液流变性的显著性变化;快速减重的程度与血液流变性的改变密切相关;快速减重对血液循环和微循环的影响,关键在于快速减重的程度,与脱水方式关系不明显。

Objective： By observing the variation of the different indices of hemorheology before and after the rapid body weight loss, this research aims to find out the effect rapid body weight loss on hemorheology. Methods： We measured the changes of hemorheology after euhydration（0%BWL）, sauna-induced and exercise-induced body weight loss by 2%（2%BWL） and by 4%（4%BWL） respectively. During the test, we utilized whole body viscosity（WBV）, plasma viscosity（PV）, hematocrit （Hct%）, erythrocyte deformability（TK）, erythrocyte aggregation indexes（A1 and A2）, erythrocyte rigid index（VR） et al. Results： （1） All indexes of hemorheology, such as WBV, PV, Hct%, TK, Fi, A1, A2, etc （P 〈 0.05）, changed significantly after 2%BWL and 4%BWL. （2） The changed indexes of hemorheology at 4%BWL are higher than those at 2%BWL （P〈0.05）. （3） The changed indexes of hemorheology of sauna-induced dehydration group are somewhat different from those of exercise-induced group. But the difference is insignificant. Conclusion： Fast body weight loss can bring the changes of hemorheology. The degree of loss may be connected with hemorheology. It is the degree of dehydration which affects the blood circulation and micro-circulation, not the means of dehydration.