摘要
目的测定精液中纤溶酶原激活物抑制剂-1(plasminogen activator inhibitor type-1,PAI-1)的含量,探讨精液的液化机制。方法分别检测门诊患者1h内不液化精液40例(A组)和1h内液化精液30例(B组)中PAI- 1的含量。结果A组PAI-1含量为(10．25±0．75)ng/ml,B组为(6．46±0．37)ng/ml,A组含量显著高于B组,P＜0．01,差异有统计学意义。精液中PAI-1含量与精液液化时间的相关性r=0．362,P＜0．01,呈正相关。结论精液中PAI-1含量升高,可导致精液液化时间延长,可作为检测精液粘稠度的一个相对指标。
Objective Discussing the mechanism of the liquefaction of semen by detecting the contents of PAI- 1 in human semen. Methods According to the liquefying time of semen, the patients were divided into two groups： Group A： 40 patients with the semen not liquefied in 60 minutes, Group B： 30 patients with the semen liquefide in 60 minutes. The contents of PAI-1 were detected by ELISA, and finally, the data were analyzed by SPSS 11.5 for windows. Results The PAI-1 content was （10.25±0.75）ng/ml in group A and （6.46±0.37）ng/ml in group B; the PAI-1 content of group A is higher than that of group B with significant difference （P〈0.01）. There is positive correlation between the PAI-1 content and the semen liquefying time （P〈0.01 ）, Conclusion The increasing of PAI-1 can delay the time of the seminal liquefaction.
出处
《中国男科学杂志》
CAS
CSCD
2006年第5期21-22,25,共3页
Chinese Journal of Andrology
基金
山东省计划生育委员会基金资助
