苯二氮类药物在住院精神病患者中使用现状

Current situation of application benzodiazepine to mental patients in hospital

目的:调查苯二氮类药物(BZD)在住院精神病患者中的应用情况。方法:对本院2004年所有住院精神病患者182例应用BZD的临床资料进行回顾性分析,对出院时仍在服用BZD的患者66例随访,用CCMD3诊断标准诊断其BZD依赖情况。结果:调查发现182例住院精神病患者中143例应用过BZD,占78.87%,其中单用1种的123例(86.01%),2种合用的20例(13.99%),药物应用依次为地西泮、艾司唑仑、阿普唑仑、氯硝西泮、劳拉西泮、硝西泮等,随访的66例患者中,因故仅随访52例,BZD依赖18例(34.62%)。结论:BZD在住院精神病患者中应用范围广泛、时间较长、剂量偏大,存在明显滥用情况,易导致患者出院后BZD依赖。

Objective： To investigate the benzodiazepine use patterns for treating mental patients in hospital. Methods： To analyze all the mental inpatients of using BZD in 2004,66 leaving hospital patients who continued using BZD were investigated, and diagnosed according to the dianostic criteria of BZD dependence （China, CCMD -3 ）. Results： 143 of 182 patients used the BZD, who were 78.87%, 123 patients used a single BZD, and 20 patients used two kinds of BZD. The kinds of using BZD were diazepam, estazolam, alprazolam, clonazepam, corazepam, nitrazepam in turn. 52 of 66 patients were visited, 18 patients were BZD dependence, who were 34.62%. Conclusions： BZD was used in wide -ranging , longer time, bigger dosage in mental inpatients, it was abused in a large dance. The patients of discharged hospital were easy dependence.