嗜麦芽窄食单胞菌呼吸道感染35例分析

Analysis of 35 cases with respiratory tract infection by stenotrophomonas maltophilia

目的探讨嗜麦芽窄食单胞菌呼吸道感染的危险因素及耐药情况。方法对35例嗜麦芽窄食单胞菌呼吸道感染的临床分析。结果35例中对复方新诺明敏感率为85.71%,对左氧氟沙星的敏感率为74.29%,对亚胺培南100%耐药,对氨基糖苷类、头孢菌素类耐药率较高。结论高龄、严重基础疾病,应用多种抗生素,院内感染应用糖皮质激素等是嗜麦芽窄食单胞菌呼吸道感染的危险因素,且对多种抗生素耐药。

Objective To inquire into risk factors that may cause infection of respiratory tract by stenotrophomonas mahophilia and the stenotraphomonas mahophilia＇ s resistance to common antibioties in order to guide clinical prevention and treatment. Methods Thirtyfive patients of respiratory tract infections by stenotraphomonas mahophilia were examined, including age and other basics of the disease. Results Among the total, the ratio of susccptivity of stenotrophomonas maltophilia to compound sulfamethoxazole was 85.17%. The ratio of susceptivity of stenotrophomonas mahophilla to levofloxaein was 82.56%. the ratio of susceptivity of stenotmphomonas mahophilia to ticarcillin/clavulanic acid was 74.29%. The ratio of resistance of stenotrophomonas mahophilia to imipenem was 100% , that is, stenotrophomonas mahophilia was totally resistant to imipenem. Stenotrophomonas mahophilia wa also highly resistant to aminoglycosides and cephalosporins. Conclusion Old age, severe basic disease, unnecessary use of antibiotics, in-hospital infection and use of glucocorticoids are main risk factors to development of respiratory tract infection by stenotmpbomonas maltophilia, which is mostly resistant to many kinds of antibiotics.