复治涂阳肺结核病人成因及疗效分析

Analysis of treatment effect and reasons for retreated smear-positive tuberculosis patients

目的 探讨WHO推荐的复治化疗方案及管理方式（DOTS）成效。方法 收集我县2003～2004年完整的复治涂阳病例74份。结果 治疗不规则或未完成疗程的4．1％，实施复治涂阳方案后2-3月末痰菌转阴率96．4％、98．6％，治愈率94．5。结论 造成复治涂阳原因是用药不合理、间断或无规律用药，未完成疗程。采用WHO推荐的8个月短程方案，严格执行DOTS，治愈复治涂阳病人合理有效。

Objective To analyze the reasons of retreated smear-positive tuberculosis patients and to explore the effects of using WHO-recommended treatment method and DOTS system. Methods Medical records of 74 retreated smear-positive TB cases were collected during the period of 2003 and 2004 in Zhanhua County. Results Among the total,4. 1% did not receive the regular treatment or did not complete the whole course of the treatment. At the end of the 2nd and 3rd month after implementing the treatment method, the rate of sputum positive-turned-negatlve were 96. 4% and 98.6% , respectively. The cure rate reached 94. 5%. Conclusion The reasons for retreated smear-positive TB cases were improper use of medication, and irregular course of treatment. The short 8 month course of treatment method as commended by WHO with strict implementation of DOTS is reasonable and effective in treating retreated smear-positive TB patients.