老年呼吸衰竭患者血清心肌酶的观察分析

Changes and clinical significance of serum enzyme levels in old patients with respiratory failure

目的观察血清心肌酶在老年呼吸衰竭患者中的变化。方法应用自动生化分析仪测定血清心肌酶、血气分析。结果呼吸衰竭组AST平均值为47.4IU/L,LDH平均值为269.8IU/L,CK平均值为178.6IU/L,CK-MB平均值为11.6IU/L;对照组AST平均值为29.2IU/L,LDH平均值为192.5IU/L,CK平均值为135.6IU/L,CK-MB平均值为6.7IU/L。两组比较,呼衰组血清心肌酶活力升高,明显高于对照组,两组比较有显著差别(P<0.01)。结论老年呼吸衰竭时血清心肌酶升高对老年呼吸衰竭患者病情严重程度和心肌受损程度以及疗效观察有一定的临床意义。

Objective To study the value of serum enzyme in old patients with respiratory failure in hospital. Methods The levels of serum enzyme in old patients with respiratory filure and the controls （ general pneumonia） were quantitatively detected by automatically particle enhanced immunoturbidimetfic assay. Results In the respiratory failure group, the average value of serum AST was 47.4IU/L, serum LDH was 269. 8IU/L, serum CK was 178.6IU/L, and serum CK-MB was 11.6IU/L. In the control group, the average value of serum AST was 29.2IU/L, serum LDH was 192.5IU/L, serum CK was 135.6IU/L, and serum CK-MB was 6. 7IU/L. the levels of serum AST, LDH, CK, Ck-Mb were significantly higher in the older patients with respiratory failure than those in the control group ： P 〈0. 005. Conclusion As respiratory failure is getting worse, serum levels of AST, LDH, CK, CK-MB were seen in gradual increase and the level in respiratory failure was significantly higher than those in the control group. The findings should be taken into consideration by clinicians when they are making diagnosis and treatment decisions.