4Koh CS, Paterson PY. Suppression of clinical signs of celltrans- ferred experimental allergic encephalomyelitis and altered cere- brovascular permeability in Lewis rats treated with a plasminogen activator inhibitor[J]. Cell Immunol, 1987,107 ( 1 ) : 52.
5Rausch M, Hiestand P,Baumann D,et al. MRI-Based Monitoringof Inflammation and Tissue Damage in Acute and Chronic Relap sing EAE[J]. Magnetic Resonance in Medicine,2003,50:309.
6]B Brochet, MSA. Deloire, T. Touil, et al. Early macrophage MRI of inflammatory lesions predicts lesion severity and disease de velopment in relapsing EAE[J]. Neurolmage, 2006,32 : 266.
7Chinet CI., Pal M, Bousquet PF, et al. Distinct spatiotemporal pattern of CNS lesions revealed by USPIO-enhanced MRI in MOG-induced EAE rats implicates the involvement of spinoolivocerebellar pathways[J]. Journal of Neuroimmunology, 2009,211:49.
8lssazadeh S,Ljungdahl A, Hojeberg B,et al. Cytokine production in the central nervous system of Lewis rats with experimental au- toimmune encephalomyelitis= dynamics of mRNA expression for interleukin-10, interleukin-12, cytolysin, tumor necrosis factor al- pha and tumor necrosis factor beta[J], 1995,61(2) :205.
9]Slavin A,Ewing C. Lin J, et al. Induction of a multiple sclerosis- like disease in mice with an immunodominant epitope of myelin oligodendrocyte glyeoprotein[J]. Autoimmunity. 1998,28 : 109.
