窄分布壳低聚糖的制备

Preparation of Narrow Distribution Oligo-Chitosan

通过微量锌盐调节氧化降解体系,制备出窄分子量分布的壳低聚糖。采用荧光探针法分析降解体系中微环境的极性差异,并用IR、GPC等对壳低聚糖产物的基本理化性质进行了初步评价。结果表明,加入3.8 mmol ZnSO4后分子量窄分布(d=1.1)的壳低聚糖(Mw=973)收率高达85%,且降解后壳聚糖基本结构单元没有发生变化。

A narrow distribution low molecular weight chitosan （LMWCTS） was prepared by the oxide degradation system adjusted with trace amount of zinc sulfate. Fluorescence probe was used to investigate the polarity of micro-area of this degradation system, IR and GPC were utilized for measuring the physic-chemical properties of these LMWCTS samples. The system with 3.8 mmol ZnSO4 had a narrow distribution of LMWCTS （^-MW =973, d = 1.1 ） and the yield of LMWCTS was 85%. Those primary structure units of the chitosan have not been altered after degradation.