针刺加微生态制剂治疗便秘型肠易激综合征临床观察

Clinical observation on acupuncture combined with microorganism pharmaceutical preparations for treatment of irritable bowel syndrome of constipation type

目的:寻找治疗便秘型肠易激综合征(IBS)的最佳方案。方法:将95例IBS病人随机分为3组,A组30例,用针刺加微生态制剂治疗;B组35例,口服润肠通便药和微生态制剂治疗;C组30例,单用针刺治疗。结果:A、B、C各组总有效率分别为90·0%、77·2%、66·7%,经统计学处理,A组与B、C组比较差异有非常显著性意义(P<0·01),B组与C组比较差异无显著性意义(P>0·05)。肠道有益菌(双歧杆菌、乳酸杆菌)与治疗前比较,3组均有不同程度升高(P<0·01,P<0·05),大肠埃希菌有不同程度降低。结论:针刺加微生态制剂治疗便秘型IBS确有较好效果,不失为治疗本病的较佳疗法。

Objective To explore the best program for treatment of irritable bowel syndrome （IBS） of constipation type. Methods Ninety-five cases of IBS were randomly divided into 3 groups. Group A （n =30） were treated by acupuncture combined with microorganism pharmaceutical preparations, group B （n =35） by oral administration of medicine for loosening the bowel to relieve constipation plus microorganism pharmaceutical preparations, and group C （ n=30） by simple acupuncture. Results The total effective rates were 90.0 %, 77.2 % and 66.7 %, in the group A, B and C, respectively, with a very significant differences as the group A compared with those in the groups B, C （P〈0.01）, and with no significant difference as the group B compared with that of the group C （P〉 0.05）. The intestinal available bacteria, bilidobacteria and lactobacillus, increased and enteric bacilli decreased in varying degrees in the 3 groups. Conclusion Acupuncture combined with microorganism pharmaceutical preparations has a better therapeutic effect on irritable bowel syndrome of constipation type.