主动脉脉压与冠状动脉病变严重程度的相关性分析

A study of relationship between coronary artery disease and aortic pulse pressure

目的探讨有创主动脉脉压(PP)水平与冠状动脉病变程度的关系。方法行冠状动脉造影术患者194(男103,女91)例;年龄(64±11)岁,造影同时测量主动脉血压。冠状动脉病变严重程度用冠状动脉病变支数及冠脉病变积分来表示。结果冠状动脉病变影响因素较多,如年龄、高血压史、糖尿病史、高血脂史等,其中冠脉狭窄组主动脉收缩压(SBP)、PP、脉压指数(PPI)显著高于非冠脉狭窄组,差异具统计学意义。其增高水平与冠脉狭窄程度呈线性关系。多因素回归分析显示:PP、年龄与冠脉狭窄程度密切相关。结论主动脉PP与冠脉病变严重程度相关,且可能是冠脉病变的独立危险因素。

AIM To study the relationship between the level of aortic pulse pressure （PP） and the degree of coronary disease. METHODS Coronary angiography （CAG） was performed in 194 patients [ 103 male, 91 female, aged from （64±11 ）years]. The aortic blood pressure was measured by computer during CAG. The degree of coronary artery disease was denoted with the coronary number of stenosis and the score of coronary lesion. RESULTS Many factors were related to coronary artery score （CAS） such as age, the history of essential hypertension, the history of diabetes, and the history of hyperlipemia. The aortic systolic blood pressure （SBP）, the aortic pulse pressure （PP） and the pulse pressure index （PPI） were significantly related to CAS （ P 〈0. 01 ）. By logistic multivariate analysis, PP was significantly related to CAS. CONCLUSION Aortic PP is one of the predictors for coronary events and a good parameter reflecting the degree of coronary artery disease （CHD）.