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恶性肿瘤自杀基因放射导向治疗的研究进展

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摘要 恶性肿瘤自杀基因放射导向治疗是近年来的研究热点。HSV-TK及EC-CD自杀基因系统是目前研究最多的两种自杀基因系统。自杀基因放射导向治疗的方法,是利用自杀基因及放疗的双重作用治疗肿瘤,通过提高放疗的敏感性,减少放疗剂量,提高治愈率,降低并发症和后遗症,提高病人的生活质量,延长病人的生存时间。用Egr-1启动子的放射诱导性进行肿瘤放射基因治疗实验研究初步获得满意效果。恶性肿瘤基因放疗具有广阔的临床应用前景。
出处 《现代肿瘤医学》 CAS 2006年第6期762-763,共2页 Journal of Modern Oncology
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