超重和肥胖对心脏结构和左室功能的影响

Influence of over weight and obesity on cardiac structure and left ventricar function

目的研究超重和肥胖对心脏结构和左室功能的影响。方法根据体质量指数(BMI)将219例体检人群分为对照组75例、超重组76例、肥胖组68例,对3组患者的彩色多普勒超声心动图检查及相关临床资料进行对比,分析超重和肥胖对心脏结构和左室功能的影响。结果肥胖组左室结构、左室舒张功能、左室收缩功能各项指标和超重组、对照组比较均有显著性差异(P<0.05),而超重组的各项指标和对照组比较无显著性差异(P>0.05)。肥胖组左室结构改变、收缩功能增强与舒张功能受损与BMI有显著相关性(P<0.05)。结论肥胖可明显加重患者左心室结构和功能损害,导致左室收缩和舒张功能下降、左室增大。

Objective It is to study the influence of over weight and obesity on cardiac structure and left ventricar function. Methods 219 people accepted health examination were divided into control group （ n = 75）, over weight group （ n = 76） and obesity group （n = 68） according to their BMI. Color Doppler echocardiogram examination result and related clinical data of the three groups were compared to analyze the influence of over weight and obesity on cardiac structure and left ventricar function. Results The indexes of left ventricar structure, left ventricar relaxing and contracting function in obesity group were significantly different with those in over weight group and control group （P 〈 0.05）. There was no significant difference in the indexes above between over weight group and control group （ P 〉 0.05 ）. The changing of left ventricar structure, strengthening of contracting function and injury of relaxing function were related with BMI （P 〈 0.05 ）. Conclusion Obesity can obviously aggravate the injury of left ventricar structure and function, so to lead to the descent of relaxing and contracting function and hypertrophy of left ventricar.