中蒙药对胆囊炎家兔抗氧化性损伤的效果比较

The Comparison in the Effects on Anti-oxidative Damage between the Mongolian Medicine and the Traditional Chinese Medicine in the Bacterial Cholecystitis of the Rabbits

目的:探讨中蒙药治疗细菌性胆囊炎的效果及血清中MDA、SOD含量的变化。方法:制备家兔细菌性胆囊炎模型,给药30天后测动物血清中MDA、SOD含量。结果:蒙药组MDA含量明显低于模型对照组和中药组,SOD含量明显高于其它各组(P<0.05)。结论:MDA、SOD含量可反映细菌性胆囊炎的氧化性损伤情况,蒙药地格达伊苏抗氧化性损伤作用优于消炎利胆片。

Objective： To investigate the curative effects of the Mongolian medicine and the traditional Chinese medicine in the treatment of the bacterial cholecystitis, and the changes in the contents of MDA and SOD in serum. Methods ： The model of the bacterial cholecystitis was made in the rabbit. To detect the contents of MDA and SOD in serum of the rabbits after administration for 30 days. Results： The content of MDA in Mongolian medicine control group was lower significantly than that in the model control group and the traditional Chinese medicine control group （P〈0. 05）. And the content of SOD in the Mongolian medicine control group was higher significantly than that in other control groups （ P〈0. 05）. Conclusion ： The contents of MDA and SOD could reflect the condition of the oxidative damage of the bacterial cholycestitis. And the effect of the Mongolian medicine, Digedayisu,surpasses Xiaoyanlidanpian on anti-oxidative damage.