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曲安奈德玻璃体腔内注射治疗白内障术后慢性黄斑囊样水肿 被引量:6

Intravitreal injection of triamcinolone acetonide for chronic cystoid macular edema after cataract operation
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摘要 目的观察曲安奈德玻璃体腔内注射治疗白内障术后慢性黄斑囊样水肿的临床疗效。方法对38例38眼白内障术后发生慢性黄斑囊样水肿的患者,行曲安奈德玻璃体腔内注射进行治疗,观察注射后1周、1月、2月、3月患者视力及黄斑中心视网膜厚度的变化及并发症。结果曲安奈德玻璃体腔内注射后,所有患者最佳矫正视力均有不同程度提高,相应的黄斑中心视网膜厚度逐渐变薄,注射后并发症包括球结膜下出血、眼压升高及黄斑囊样水肿复发。结论曲安奈德玻璃体腔内注射对白内障术后慢性黄斑囊样水肿是一种安全、有效的治疗方法,但黄斑囊样水肿复发的原因及再次治疗时机有待进一步观察。 Objective To investigate the clinical therapeutic effect of intravitreal injection of triamcinolone acetonide(TA) for chronic cystoid macular edema after cataract operation. Methods Thirtyeight cases (38 eyes) with chronic cystoid macular edema after cataract operation were performed intravitreal injection of TA and the visual acuity, macular retinal thickness and complication were observed in 1 week, 1 month, 2 months, 3 months after injection. Results Visual acuity in all cases was improved to different degrees after TA injection, accordingly, macular retinal thickness was decreased. Complications after injection included sub-conjunctive hemorrhage, elevating intraocular pressure and recurrent cystoid macular edema. Conclusion Intravitreal injection of TA is an effective , safe therapeutic method for chronic cystoid macular edema after cataract surgery. But the cause and the therapeutic time of recurrent cysoid macular edema will be observed further.
出处 《眼科新进展》 CAS 2006年第6期450-451,共2页 Recent Advances in Ophthalmology
关键词 白内障 黄斑囊样水肿 曲安奈德 cataract cystoid macular edema triamcinolone acetonide
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参考文献5

  • 1Flach AJ. The incidence, pathogenesis and treatment of cystoid macular edema following cataract surgery [J].Trans Am Ophthmol Soc 1998;96:557-634.
  • 2Levin DS, Lira JI. Update on pseudophakic cystoid maudar edema treatment options[J]. Oph Cli Nor Ame 2002;15: 467-472.
  • 3Conway MD, Canakis C, Livir-Rallators C. Intravitreal tricamcinolone acetonide for refractory chronic pseudophakic cystoid macular edema[J]. J Cataract Refract Surg 2003;29:27-33.
  • 4Jonas JB, Kreissig I, Sofker A. Intravitreal injection of triamcinolone for diffuse diabetic macular edema [J].Arch Ophthalmol 2003; 121:57-61.
  • 5刘谊,严密.曲安奈德玻璃体腔注射的临床应用[J].中华眼底病杂志,2003,19(4):263-265. 被引量:89

二级参考文献4

  • 1Jost B. Jonas,Ingrid Kreissig,Robert F. Degenring. Intravitreal triamcinolone acetonide as treatment of macular edema in central retinal vein occlusion[J] 2002,Graefe’s Archive for Clinical and Experimental Ophthalmology(9):782~783
  • 2Taiji Sakamoto,Miho Miyazaki,Toshio Hisatomi,Takao Nakamura,Akifumi Ueno,Keiko Itaya,Tatsuro Ishibashi. Triamcinolone-assisted pars plana vitrectomy improves the surgical procedures and decreases the postoperative blood–ocular barrier breakdown[J] 2002,Graefe’s Archive for Clinical and Experimental Ophthalmology(6):423~429
  • 3Yu-sheng Wang,Ulrike Friedrichs,Wolfram Eichler,Stephan Hoffmann,Peter Wiedemann. Inhibitory effects of triamcinolone acetonide on bFGF-induced migration and tube formation in choroidal microvascular endothelial cells[J] 2002,Graefe’s Archive for Clinical and Experimental Ophthalmology(1):42~48
  • 4Yan-Nian Hui,Hou-Cheng Liang,Yong-Shu Cai,Bernd Kirchhof,Klaus Heimann. Corticosteroids and daunomycin in the prevention of experimental proliferative vitreoretionopathy induced by macrophages[J] 1993,Graefe’s Archive for Clinical and Experimental Ophthalmology(2):109~114

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