孕妇外周血中胎儿有核红细胞用于产前诊断的研究进展

Research advances in the prenatal diagnosis by separating fetal nucleated red blood cell from maternal peripheral blood.

本文概述孕妇外周血中胎儿有核红细胞的分离与检测用于产前诊断的研究状况,描述母体外周血中的胎儿细胞的特点,胎儿有核红细胞的富集和分离方法,并对各方法的优点、缺点、病理性妊娠的意义、临床应用、存在的问题及研究进展作一综述。

The article summarizes the inspection status of separating fetal nucleated red blood cell from-maternal peripheral blood in prenatal diagnosis. Describes the fetal cell characteristics in maternal peripheral blood, methods of enrichment and isolation. And reviews the advantage and disadvantage of inspection method. The sense of pathological pregnancy. The usefulness of clinical appliance. The existing problems and research advances.